Compared with patients with higher serum uromodulin levels, those with lower uromodulin levels were older, had a higher proportion of previous history of smoking, diabetes, and cardiovascular disease, higher proportion of current use of antihypertensive medications, and had higher levels of blood pressure, triglyceride, high-sensitivity C-reactive protein and urinary albumin/creatinine ratio but lower levels of total cholesterol and eGFR. Here, UMOD is linked to diabetes mellitus.