MAPT and Alzheimer disease: pS396 tau was slightly reduced in the detergent-soluble fraction for DNA Aβ42 trimer- and Aβ42 peptide-immunized female mice compared with 3xTg-AD female control mice (889.2 ± 273.2 pg/mg, 1264 ± 389.1 pg/mg, and 1441 ± 566 pg/mg, respectively; p = ns by one-way ANOVA).