Notably, we also detected a significant (p = 0.001), almost 90% reduction of serum ZO concentration as shown in Figure 2A. Table 3 demonstrates that serum ZO correlated with the degree of fatty liver (i.e., with Hamaguchi score (p = 0.037) serum AST (p = 0.041) and ALT (p = 0.043)), total lipids (p = 0.041), as well as low-density lipoprotein (p = 0.029). Here, GPT is linked to fatty liver disease.