INS and Insulin resistance: The matter is relevant because insulin resistance and hyperinsulinemia, unfortunately, intertwined with type 2 diabetes, are considered risk factors for cancer, and this risk has been linked to the insulin hyper-activation of phosphatidylinositol kinase (PI3K)/α-serine/threonine kinase (AKT)/mTOR Complex 1/mTORC1) signalling [26].