In order to decipher the molecular mechanisms via which M20 and D-A10 MAb limited the growth of Isreco-1 tumors, we performed immunohistochemistry (IHC) staining and quantification of Ki67 and Casp3A, which revealed that D-A10 and M20 exhibited distinct anti-tumor growth effects. This evidence concerns the gene MKI67 and neoplasm.