CCR6 and atopic conjunctivitis: In mice induced with experimental allergic conjunctivitis (EAC), disease severity was compared between WT and CCR6 knockout (KO) models which showed the absence of CCR6-suppressed, allergen-specific immunoglobulin-E (Ig E) secretion, decreased mast cell and eosinophil accumulation, and therefore, minimized allergic conjunctival inflammation.