Next, we investigated potential regulators of the observed increase in astrocytic TRPM7 expression by exposing primary cortical rat astrocytes to various pro‐inflammatory stimuli known to be abundantly present in MS lesions and reported to have an effect on astrocyte function (Becher et al., 1999; Liddelow et al., 2017; Mizee et al., 2014; van Horssen et al., 2006). This evidence concerns the gene TRPM7 and myeloid sarcoma.