Our stratified analysis showed that, compared with each wild type, AA genotype of ERCC1 rs3212986 increased the risk of NSCLC in male population (OR = 3.246; 95% CI: 1.375‐7.663), meanwhile CC genotype of OGG1 rs1052133 in female ones(OR = 2.588; 95% CI: 1.035‐6.474). This evidence concerns the gene ERCC1 and non-small cell lung carcinoma.