ERCC1 and cancer: Mutations in 3ʹUTR of key DNA repair enzyme genes can contribute to interindividual differences in DNA repair efficiency, which has a crucial role in hereditary susceptibility to cancer risk and chemotherapy resistance.16 In our previous study, two SNPs in ERCC1 were investigated used HPLC and modified comet assay to evaluate the individual capacity of repairing BPDE‐DNA adduct from 117 randomly selected healthy participants.