HAND2 and neuroblastoma: We integrated the ChIP-seq tracks for TBX2 with those reported for GATA315,34, HAND2, PHOX2B15, and MYCN (this study) in NB cell lines and observed overlap of TBX2 peak summits with binding sites of these CRC transcription factors (Fig. 3b), thus supporting the notion that TBX2 is indeed actively taking part in this CRC.