A number of the FOXM1 G2/M target genes are of particular interest, i.e. BRIP1 and RRM2 which are implicated in control of replicative stress in NB (unpublished data), RAD51 implicated in homologous DNA repair and FANCI, FANCD2 and FANCG involved in replication fork stability and interstrand cross-link DNA repair. Here, RRM2 is linked to neuroblastoma.