Motor dysfunction measured on the UPDRS III was not significantly different in a Spanish LRRK2 cohort in those who converted to PD compared to non‐converters at baseline, although in those that went on to convert to PD within 4 years there was significant worsening of the UPDRS III scores from a mean of 9.3 at baseline to 25 compared to 0.8 to 1.6 in the non‐converting group (although the number of converters was small) (Sierra et al., 2017). This evidence concerns the gene LRRK2 and Parkinson disease.