However, after removing Cargnin’s study, the significant association between GRIA1 rs2195450 C>T polymorphism and migraine risk was observed under homozygous model (TT vs. CC, OR = 1.73, 95%CI = 1.25–2.40, PZ = 0.009), heterozygous model (CT vs. CC, OR = 1.33, 95%CI = 1.08–1.65, PZ = 0.007), dominant model ((TT+CT) vs. CC, OR = 1.45, 95%CI = 1.19–1.76, PZ = 0.0002), and allelic contrast model (T vs. C, OR = 1.46, 95%CI = 1.12–1.91, PZ = 0.005). This evidence concerns the gene GRIA1 and migraine disorder.