HMGB3 and non-small cell lung carcinoma: The results of Western blot analysis showed that the protein level of HMGB3 in 30 cases of NSCLC tissues was higher than that in the adjacent tissues, along with 20 cases with a significantly higher HMGB3 protein level (>two-fold increase) than the adjacent tissues (P<0.05) (Figure 2B,C).