Otherwise, in the multivariate Cox regression models for fatal and non-fatal cardiovascular events, serum Angpt-2 remained an independently predictive factor when adjusting for age, male gender, diabetes, LDL cholesterol, LVMI and components of MIAC syndrome (hs-CRP, serum albumin, background VC and background AVD) (p = 0.02, Table 5). The gene discussed is ALB; the disease is diabetes mellitus.