TP53 and cervical cancer: Due to the fact that Kpnβ1 is involved in the nuclear import of proteins involved in apoptosis induced by chemotherapy, such as p53 [9, 28, 29], and since overexpression of Kpnβ1 alters the proliferation and cell cycle progression of cervical cancer cells, we next investigated whether Kpnβ1 overexpression may influence the effectiveness of cisplatin, an anticancer chemotherapy commonly used to treat patients with cervical cancer.