EGFR and non-small cell lung carcinoma: A phase III trial confirming the effect of osimertinib in NSCLC patients with the EGFR T790M mutation (AURA3 trial) showed superiority of osimertinib over platinum therapy plus pemetrexed regarding PFS (HR, 0.30; 95% CI, 0.23 to 0.41; p < 0.001; 10.1 vs. 4.4 months, respectively) [30].