ANGPT4 and diabetes mellitus: In mouse, excess of exogenous Angpt4 or ANGPT4 similarly induced blood and lymphatic vascular remodeling (Kim et al., 2007; Lee et al., 2004) and ANGPT4 improved vascular function in streptozotocin-induced model for diabetes (Kwon et al., 2013), suggesting that Angpt4, ANGPT4 and Angpt1 have similar functions.