CD8A and ischemic stroke: Previous studies indicated that ischemic stroke increases IL‐2 levels in the periphery.30 Because IL‐2 plays a critical role in regulating CD8+ T cell activation, and CD8+ T cell activation is detrimental for myelinated neural fibers, we hypothesized that neutralization of IL‐2 with IL‐2mAb may be protective against demyelination in the late phase of cerebral ischemic injury.