Stroke elicits profound immune responses in both periphery and brain, which have been shown to play critical roles in aggravating ischemic brain injury and lymphocytes are one of the major cell types that affects ischemic brain injury..32 IL‐2 is a critical regulator of lymphocyte homeostasis and function, as well as a powerful stimulant for T lymphocytes and NK cells.19 Accordingly, we isolated brain‐invading leukocytes from the hemisphere of IgG and IL‐2mAb‐treated mice 7 days after dMCAO and analyzed leukocyte subsets by flow cytometry (Figure 4A). Here, IL2 is linked to Stroke.