WT1 and chronic myelogenous leukemia, BCR-ABL1 positive: Specifically, in a chronic myelogenous leukemia cell line, ZNF224 was shown to augment the signaling of Wilms’ Tumor 1 (WT1), which is a known TSG that controls the expression of genes involved in differentiation, apoptosis, and cell cycle progression (Florio et al., 2010).