This relation had been already shown in non‐small cell lung cancer (NSCLC), where miR‐197 blocks the cyclin‐dependent kinase CKS1B, which is linked to PD‐L1 expression through STAT3 signal.28 Jingjing et al56 reported that protein level of PD‐L1 in OSCC cell line is higher than normal oral mucosa cell line, while no differences were highlighted in the PD‐L1 mRNA. This evidence concerns the gene STAT3 and non-small cell lung carcinoma.