In this order, with respect to the management, European Renal Best Practice (ERBP) [14] recommends pre-procedure assessment of creatinine concentrations and thus identifying high-risk patients—mostly patients with chronic kidney disease, diabetes mellitus, older age, use of intra-aortic balloon pumps [15], cardiovascular diseases, and people with high C-reactive protein (CRP) levels [16]—to whom a repeat serum creatinine test 12 and 72 hours after administration of the contrast media should be performed. The gene discussed is CRP; the disease is diabetes mellitus.