The concentration of homocysteine (Hcy), glutathione (GSH), 8-oxo-2’-deoxyguanosine (8-oxo2dG) and 8-oxoguanine DNA glycosylase (OGG1) in plasma of Alzheimer’s disease (AD) patients and related (RC) and unrelated controls (UC), stratified according to APOC1’638 genotype. The gene discussed is OGG1; the disease is Alzheimer disease.