The microarray data (gLOG data; Hartmann et al. 2009) from fresh frozen (FF) tissue of high-risk breast cancer patients (Fig. 1; n = 204) were converted by mathematical calculation with 2exp(gLOG) function into PITX2 PMRcalc data and used to determine the best PITX2 cut-off value (PMRcalc) for DFS as shown in Fig. 2a. This evidence concerns the gene PITX2 and breast cancer.