While Luminal® delayed necroptosis, the more potent structural analogue phenytoin (Phenhydan®), which is widely used as antiepileptic, as well as in a broad spectrum of neurologic disorders [21], protected murine L929 cells from TNF-induced cell death in a dose-dependent manner, and for longer time points (Fig. 1g). The gene discussed is TNF; the disease is nervous system disorder.