The single ΔkguT and the double ΔgntP ΔkguT mutants were slightly more virulent than PAO1 in C. elegans. Thus, the bacterial ability to import (and use) glucose, as well as the accessory function of the glucose uptake transporters in the regulation of cell metabolism highlighted in this study, may have a different relevance in different infection models. Here, SMOX is linked to infection.