The subject headings were Mucopolysaccharidosis I, Mucopolysaccharidosis II, Mucopolysaccharidosis IV, and Mucopolysaccharidosis VI, MPS I, MPS II, MPS IV, MPS VI, enzyme replacement therapy, ERT, laronidase and Aldurazyme, idursulfase and Elaprase, elosulfase and Vimizim, galsulfase and Naglazyme. The gene discussed is IDS; the disease is mucopolysaccharidosis type 6.