Specific IDH1 mutations lead to discriminable protein profiles for low-grade glioma (sdis = − 0.47; p = 0.0; srand = − 3.1e−6) and glioblastoma (sdis = − 1.59; p = 5.0e−4; srand = − 1.0e−5). Here, IDH1 is linked to central nervous system cancer.