Analysis of the available results indicated that lncRNAs may be involved in important biological processes and cellular pathways connected with direct response to irradiation and chemo exposure such as cell cycle, apoptosis, RAS pathway, and p53 pathway, with cell phenotype and cancer initiating cells such as cadherin, Wnt, TGF-beta, EGFR, and Notch signaling pathways as well as angiogenesis, Table 7. Here, TP53 is linked to cancer.