To evaluate whether LDHB could be a potential target of miR-375 in MCC, we quantified miR-375 and LDHB expressions in three MCPyV− (MCC13, MCC14/2, and MCC26) and MCPyV+ (MKL-1, MKL-2 and WaGa) MCC cell lines using RT-qPCR and Western blotting, respectively. This evidence concerns the gene LDHB and Merkel cell skin cancer.