For the discrimination between DLB and AD, we found that low levels of tau (OR, 0.22; 95% CI, 0.10‐0.50) and high levels of o‐α‐syn (OR, 2.67; 95% CI, 1.03‐6.94) give a higher risk for DLB compared with AD. Here, MAPT is linked to Alzheimer disease.