Interestingly, we identified statistically significant co-expression of CRB3 with EPB41L4B and/or EPB41L5 in several microarray studies of cell line panels [15–17], across the entire cell line panel of the Cancer Cell Line Encyclopedia [18], as well as a study of 21 primary human mammary epithelial cell lines [19] (Table 1). This evidence concerns the gene CRB3 and cancer.