IL10 and infection: Infection with EHV-1 Ab4 induced an intranasal cytokine response characterized by a sharp increase in IFN-α on d2pi (p<0.0001) and elevated IL-10 staring on d2pi (p<0.01) on d2pi compared to the Ab4ΔORF1/71 infected and non-infected control groups (Fig 2A and 2B).