AKT1 and seminoma: Previously, we have found that the sensitivity of seminoma to CDDP is regulated by TDRG1 (testis developmental related gene 1), an oncogene that is exclusively expressed in testis and can promote the proliferation and progression of human seminoma cells through PI3K/Akt/mTOR signaling.5, 6 However, the mechanisms underlying the gain of function of TDRG1 in seminoma and CDDP‐resistance context remains to be determined.