Among the 421 male participants, 2.9% of BRCA1 PV carriers and 6.2% of BRCA2 PV carriers were diagnosed with prostate cancer at inclusion (mean age at diagnosis for BRCA1: 61.5, range 48–71 and 64.1, range 50–78 for BRCA2). This evidence concerns the gene BRCA1 and prostate cancer.