With respect to BRCA2, 61.1% of female PV carriers had BC (mean age at diagnosis: 43.6, range 21–90), 10.1% had OC or fallopian tube cancer (mean age at diagnosis: 57.9, range 31–99) and 32.9% were free of these cancers (mean age at inclusion: 42.1, range 19–91). This evidence concerns the gene BRCA2 and cancer.