More recently, post-mortem assessment of T cells from patients who died from severe sepsis showed almost no production of IFNγ, TNFα, IL-6, and IL-10 after anti-CD3/CD28 mAb stimulation compared to samples from non-septic, control patients (36)—further supporting the idea that sepsis affects general T cell function. The gene discussed is TNF; the disease is Sepsis.