ANXA2 and autoimmune polyendocrinopathy: Besides the well investigated three “criteria” aPLs, a growing number of “non-criteria” antibodies against various biomolecules, such as prothrombin/phosphatidylserine, vimentin/cardiolipin, protein S, protein C, annexin A2 (AnxA2), annexin A5 (AnxA5), oxidized low-density lipoproteins, lysobisphosphatidic acid, and sulfatides, have been linked to the occurrence of APS (7).