Antiphospholipid antibodies titers are used for diagnosis of APS according to the revised Sapporo criteria (> 40 IgM phospholipid units [MPL] or > 40 IgG phospholipid units [GPL]; here, one unit is defined as one microgram of antibody per milliliter or > 99th percentile for aCL and > 99th percentile for anti-β2GPI) (3, 5). The gene discussed is CD40LG; the disease is autoimmune polyendocrinopathy.