Further, when comparing IBS subtypes (IBS-D, IBS-C, and IBS-nonCnonD), there were no differences in fecal protein levels or mucosal mRNA expression of CgA, CgB, SgII or SgIII between the IBS subtypes (R2 = 0.03, Q2 = −0.05). The gene discussed is CGA; the disease is irritable bowel syndrome.