CD14 and chronic myelomonocytic leukemia: We found that accumulation of classical monocytes (cMo) CD14++CD16− analyzed by flow cytometry, at the expense of intermediate monocytes (iMo) CD14++CD16+ and nonclassical (ncMo) CD14−/lowCD16+, can be a powerful tool to diagnose CMML, regardless of mutational background, subtype, or dysplastic versus proliferative features.