Low FBP1 expression was significantly correlated with alpha-fetoprotein (AFP) ≥ 20 ng/ml (P = 0.026), portal vein tumour thrombus (PVTT) (P = 0.020), satellite nodule (P = 0.006), advanced TNM stage (P = 0.001) and advanced Barcelona Clinic Liver Cancer stage (BCLC stage; P = 0.001) (Table 1). The gene discussed is AFP; the disease is liver cancer.