In this work, we aimed to examine the association of IL6 rs1800795, IL6 rs1800796, IL6 rs1800797, IL10 rs1800896, IL10 rs3021097, NFKB1 rs28362491, NFKBIA rs2233406, NFKBIA rs696, IL18 rs1946518, IL18 rs187238, TNF rs1799964 and TNF rs1800629 polymorphisms with AKI risk among the pediatric population in China. The gene discussed is TNF; the disease is acute kidney injury.