Lipomas (single or multiple) were the most common skin lesion (37/53) affecting 37 patients (25.52% of MEN1 affected patients and 69.81% of all skin lesions), both alone (20 cases) or in combination with other skin lesions (7 cases; 5 with angiofibromas, one with angiomas and one with angiofibromas and fibromas). The gene discussed is MEN1; the disease is Angiofibromas.