EGFR and lung adenocarcinoma: For example, Chiu et al. claimed that both gefitinib and erlotinib are active in lung adenocarcinoma patients with G719X/L861Q/S768I mutations but they had short PFS (a median of 7.7 months) than in those with common EGFR mutations (a median of 11.4 months) (p < 0.01) [13].