However, we did detect significant increases in the percentage of neutrophils (CD11b+Ly6G+F4/80−Gr-1−) in the BALF and lungs of HO-1−/− mice compared to HO-1+/+ mice at 6, 12, and 18 weeks post-infection (Figures 5N and 5O). This evidence concerns the gene HMOX1 and infection.