Similar results were found during an analysis of 280 patients with suspected bacteremia by Watanabe et al, where PCT concentrations were significantly higher in blood culture-positive cases (n = 55) than blood culture-negative cases (n = 235) (6.0±28.4 vs 0.29±0.5, respectively, P = 0.03) [28].Data analysis revealed that at a value of 3.05 ng/mL, the sensitivity and specificity of PCT for septic shock was found to be 63% and 65% respectively. Here, CALCA is linked to bacterial infectious disease with sepsis.