DNM2 and centronuclear myopathy: Cytosolic DNM2 accumulation could also be observed in transfected mammalian myoblasts (R369W, R465W, and R522H) [53], in the body wall muscle of Drosophila larvae stably expressing DNM2 mutant proteins (R465W, A618T, and S619L) [52], and in muscle biopsies of CNM patients (D614N) [46].