S100B and neuromyelitis optica: In the cerebrospinal fluid (CSF) of patients with neuromyelitis optica (NMO), the levels of S100B and GFAP are higher than those in the CSF of patients with MS and other noninflammatory neurological disorders (OND) and correlate with Expanded Disability Status Scale (EDSS) during attack and the length of spinal cord lesion [6, 7].