LGALS3 and leptospirosis: Although several mechanisms have been implicated (including Gal-3 recognition of pathogen-associated molecular patterns such as lipopolysaccharide, microbe binding to target cells and chemoattraction by phagocytes Sato et al., 2014; Subhash et al., 2016), the specific mechanism(s) involved in leptospirosis require further studies to be clarified.