Corticosteroids inhibit various cytokines in TB (IFN-γ, TNF-α, IL-1β) and TB-IRIS (IL-6, IL-10, IL-12p40, TNF-α, IFN-γ, and IP-10) (Mahuad et al., 2004; Mayanja-Kizza et al., 2005; Meintjes et al., 2012; Bongiovanni et al., 2015). This evidence concerns the gene IL1B and tuberculosis.