It is well documented that the ABC transporters expressed on cancer cell membrane are responsible for MDR, which finally leads to the failure of chemotherapy (Dassa and Bouige, 2001; Szakács et al., 2006; Shukla et al., 2008; Stavrovskaya and Stromskaya, 2008; Eckford and Sharom, 2009; Kartal-Yandim et al., 2016). The gene discussed is ABCG2; the disease is cancer.