KLK3 and neoplasm: Patients with bone metastases were significantly older (70 vs. 65 years, interquartile range: 62–77 vs. 59–71, p < 0.001), more frequently had a PSA value >20 ng/ml (57.5 vs. 7.4%, p < 0.001), more frequently harboured clinical tumour stage T3 to T4 (20.2 vs. 2.4%, p < 0.001) and more frequently harboured GGG 5 (54.1 vs. 6.3%, p < 0.001).