In search of the genetic cause of the underlying PID of patient II.2, we performed a previously described PID targeted NGS approach14, including STAT3 and DOCK8. A homozygous single nucleotide variant in the ATM gene (c.1010 G > A, p.R337H) was detected and ruled-out to be disease-causing by normal radiation sensitivity testing of fibroblasts of patient II.2 and later a normal ATM sequence of patient II.3. The gene discussed is ATM; the disease is pelvic inflammatory disease.